Position Summary
- Seeking a motivated and experienced bench scientist to join its Retinal and Vascular Biology group.
- This one-year contract opportunity will contribute to the development of innovative therapeutics for retinal diseases while collaborating with multidisciplinary teams across Cambridge, South San Francisco, and the broader company's research network.
- The ideal candidate will have extensive industry experience developing and executing in vitro biochemical and cell-based assays, supporting compound screening workflows, and evaluating pharmacological activity.
- Strong expertise in cell culture, cellular biology, assay optimization, and scientific data analysis is essential.
Responsibilities:
- Perform complex in vitro assays to evaluate endothelial biology, including barrier function, transport, angiogenesis, differentiation, and cellular specialization.
- Culture and maintain primary and immortalized cells for use in in vitro assays.
- Develop, optimize, and execute in vitro biochemical and cell-based assays to support compound screening and therapeutic research.
- Test compounds representing diverse mechanisms of action and characterize their pharmacological activity.
- Support assay validation, optimization, compound handling, and screening workflows.
- Analyze and interpret experimental data to evaluate results and identify meaningful scientific findings.
- Present experimental data and communicate research findings to project teams.
- Develop and optimize in vitro vascular integrity assays.
- Participate in team meetings and scientific discussions focused on retinal disease research and therapeutic target discovery.
- Maintain accurate, detailed records in electronic laboratory notebooks.
- Follow established laboratory procedures and adhere to safe laboratory practices.
Qualifications:
Education:
- Bachelor's or Master's degree in Biological Sciences.
Experience:
- Minimum of 5 years of industry experience in in vitro biochemical and cell-based assay development and execution.
- Industry experience supporting compound handling and screening workflows.
- Strong hands-on laboratory experience in cell culture and cellular biology techniques.
- Experience developing and executing in vitro assays to support compound screening, validation, and optimization.
- Ability to analyze, interpret, and communicate scientific data and findings effectively.
- Strong organizational skills and attention to detail.
- High level of motivation, scientific curiosity, and passion for research.
Preferred Qualifications:
- Familiarity with retinal biology, vascular biology, and inflammation.
- Experience culturing primary endothelial cells or retinal epithelial cells.